Table 5.
Partial Correlation of Average RNFL Thickness of both Eyes and T-cell Counts or Cytokine Levels in all Participants and in Patients with POAG, Adjusted for Age
| All participants (POAG and controls) | Partial correlation coefficient (r) | P value |
|---|---|---|
| HSP27 stimulated Th1 cells (%, [n = 20 controls and 28 POAG]) | -0.31 | 0.03 |
| HSP27 stimulated Treg cells (%, [n = 21 controls and 29 POAG]) | -0.11 | 0.44 |
| α-crystallin–stimulated Th1 cells (%, [n = 13 controls and 20 POAG]) | -0.52 | 0.002 |
| α-crystallin–stimulated Treg cells (%, [n = 13 controls and 20 POAG]) | -0.26 | 0.14 |
| Interferon-γ (pg/ml, [n = 32 controls and 31 POAG]) | -0.72 | < 0.001 |
| Patients with POAG | Partial correlation coefficient (r) | P value |
|---|---|---|
| HSP27-stimulated Th1 cells (%, [n = 28]) | -0.19 | 0.34 |
| HSP27-stimulated Treg cells (%, [n = 29]) | -0.07 | 0.72 |
| α-crystallin–stimulated Th1 cells (%, [n = 20]) | -0.09 | 0.71 |
| α-crystallin–stimulated Treg cells (%, [n = 20]) | -0.24 | 0.31 |
| Interferon-γ (pg/ml, [n = 31]) | -0.31 | 0.09 |
Significant P values are in bold.
HSP = heat shock protein; POAG = primary open-angle glaucoma; RNFL = retinal nerve fiber layer; Th1 cells = T helper type 1 cells; Treg cells = regulatory T cells