Table 6.
Clinical trials on collagen-based scaffolds in NTE. (NA: Not applicable).
| ClinicalTrials.gov identifier | Transplant method | Injury site | Injury type | Phase | Country | Reference |
|---|---|---|---|---|---|---|
| NCT02510365 | Necrohemorrhagic tissues removal followed by transplanted with MSCs | Thoracic and cervical | Acute complete SCI | 1 | China | [246] |
| NCT02352077 | Scar tissues removal followed by transplanted with human umbilical cord MSCs or BMMCs | Thoracic and cervical | Chronic complete SCI | 1 | China | [247,248] |
| NCT02688049 | Scar tissues removal followed by transplanted with MSCs or NSCs | Thoracic and cervical | Chronic complete SCI | 1 and 2 | China | [249] |
| NCT02688062 | Scar tissues removal followed by transplanted with BMMCs | Thoracic | Chronic complete SCI | 1 and 2 | China | Clinicaltrials.gov |
| NCT01884376 | Implantation of Neuromaix during a diagnostic nerve biopsy | Sural nerve | PNI | NA | Germany | [250] |
| NCT01809002 | Implantation of bovine collagen-based nerve cuff | Peripheral nerve | PNI | 3 | America | Clinicaltrials.gov |
| NCT04353908 | Subcutaneous collagen injection of porcine origin | Facial nerve | PNI | NA | Italy | [251] |