Table 1.

Patient Characteristics

		All	Phase I	Phase II Untreated	Phase II Pre-Treated
Category	Subgroup	64 (100%)	31 (49%)	15 (23%)	18 (28%)
Age - median (min,max)		64 (40,84)	64 (46,84)	65 (40,73)	64 (52,80)
Gender
	Female	28 (44%)	21 (68%)	10 (67%)	8 (44%)
	Male	36 (56%)	10 (32%)	5 (33%)	10 (56%)
Race/Ethnicity
	White/Non-Hispanic	51 (80%)	26 (84%)	11 (73%)	14 (78%)
	Black/Non-Hispanic	10 (16%)	4 (13%)	3 (20%)	3 (16%)
	Asian-PI/Non-Hispanic	2 (3%)	0 (0%)	1 (7%)	1 (6%)
	Any/Hispanic	1 (1%)	1 (3%)	0 (0%)	0 (0%)
ECOG
	0	16 (25%)	7 (23%)	4 (27%)	5 (28%)
	1	45 (70%)	23 (74%)	9 (60%)	13 (72%)
	2	3 (5%)	1 (3%)	2 (13%)	0 (0%)
Prior Platinum
	Yes	17 (27%)	7 (23%)	0 (0%)	10 (56%)
	No	47 (73%)	24 (77%)	15 (100%)	8 (44%)
Family History
	Yes	44 (69%)	12 (39%)	15 (100%)	17 (94%)
	No	20 (31%)	19 (61%)	0 (0%)	1 (6%)
Known HR-DDR mutation
	Yes	19 (30%)	2 (6%)	5 (33%)	12 (67%)
	No	45 (70%)	29 (94%)	10 (67%)	6 (33%)