Skip to main content
. 2023 Apr 26;66(9):6414–6435. doi: 10.1021/acs.jmedchem.3c00541

Figure 9.

Figure 9

Initial PK characterization of compounds 15d and 21d, as well as their metabolites 14 and 20 after IV injection of compounds 15d and 21d, respectively. (A) Plasma and brain concentration–time curve of compound 15d; (B) plasma and brain concentration–time curve of compound 14; (C) plasma and brain concentration–time curve of compound 21d; (D) plasma and brain concentration–time curve of compound 20; (E) selected PK parameters of compound 15d; (F) selected PK parameters of compound 14; (G) selected PK parameters of compound 21d; and (H) selected PK parameters of compound 20.