Table 8.
Multiplicative and additive models of association between two single nucleotide polymorphisms and risk of ischemic stroke.
| SNP | Male |
Female |
||
|---|---|---|---|---|
| OR (95%CI)* | p value | OR (95%CI)* | p value | |
| rs10739971 (GA or AA vs GG) | 1.561 (1.048–2.325) | 0.028 | 0.810 (0.526–1.247) | 0.338 |
| rs17276588 (GA or AA vs GG) | 5.978 (4.500–7.941) | < 0.001 | 3.238 (2.463–4.256) | < 0.001 |
| Multiplicative model | 1.624 (1.022–2.580) | 0.040 | 2.155 (1.269–3.663) | < 0.001 |
| Additive model | 5.746 (4.207–7.849) | < 0.001 | 5.652 (4.028–7.932) | < 0.001 |
*ORs and 95% CIs calculated by logistic regression.
SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval.