Table 2.

HScore for the diagnosis of HLH.

HScore	Value
Presence of immunosuppression (no: 0 points; yes: 18 points)	18
Fever (<38.4°C: 0 points; 38.4–39.4°C: 33 points; >39.4°C: 49 points)	49
Organomegaly (no: 0 points; splenomegaly or hepatomegaly: 23 points; splenomegaly and hepatomegaly: 38 points)	0
Elevation in triglyceride concentrations (g/L) (<1.5: 0 points; 1.5–4: 44 points; >4: 64 points)	0
Elevation in ferritin concentrations (µg/L) (<2000: 0 points; 2000–6000: 35 points; > 6000: 50 points)	35
Elevation in aspartate aminotransferase concentrations (U/L) (<30: 0 points; ≥30: 19 points)	19
Low fibrinogen concentrations (g/L) (>2.5: 0 points; ≤2.5: 30 points)	0
Presence of cytopenia (1 lineage: 0 points; 2 lineages: 24 points; 3 lineages: 34 points)	34
Hemophagocytosis in a bone marrow aspirate (no: 0 points; yes: 35 points)	35