. 2023 Apr 18;14(5):591–598. doi: 10.1021/acsmedchemlett.2c00514

Table 1. Biochemical and Cellular Evaluation of First Subset of 2-Aminopyrimidines Based EGFR Inhibitors^a.

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EGFR wild-type (WT), L858R (LR), and L858R/C797S (LR/CS) were measured by HTRF-Assay. EGFR-L858R and EGFR-L858R/C797S dependent Ba/F3 cells were measured by CTG assay.

Table 1. Biochemical and Cellular Evaluation of First Subset of 2-Aminopyrimidines Based EGFR Inhibitorsa.

Table 1. Biochemical and Cellular Evaluation of First Subset of 2-Aminopyrimidines Based EGFR Inhibitors^a.