Table 3.

Association between quality of life and tobacco use adjusted for age and gender

	Physical Functioning ≥ 88a		Bodily Pain ≥ 75a		General Health ≥ 76a		Vitality ≥ 69a
	(n = 1246)		(n = 1244)		(n = 1247)		(n = 1244)
	OR (95%CI)	p-value	OR (95%CI)	p-value	OR (95%CI)	p-value	OR (95%CI)	p-value
Pack-year 10	0.72 (0.64–0.82)	5.4 × 10 −7	0.89 (0.79–1.0)	0.056	0.75 (0.66–0.85)	0.000005	0.71 (0.62–0.81)	1.3 × 10 −7
Box-year 10	0.99 (0.96–1.0)	0.53	0.95 (0.91–0.98)	0.00078	0.99 (0.96–1.0)	0.29	0.96 (0.93–0.99)	0.0066
Female gender	0.58 (0.43–0.79)	0.00042	0.77 (0.61–0.98)	0.033	0.85 (0.67–1.1)	0.20	0.64 (0.50–0.81)	0.00027
Age 10 yr	0.70 (0.62–0.78)	3.3 × 10 −10	0.92 (0.85–1.0)	0.058	0.91 (0.83–0.99)	0.03	1.1 (1.1–1.2)	0.0017
Model validation
Overall performance
Nagelkerke R Square	0.12		0.027		0.041		0.048
Discrimination
AUCb	0.69 (0.65–0.72)	6.9 × 10 −22	0.58 (0.55–0.61)	8.7 × 10 −7	0.60 (0.56–0.63)	1.1 × 10 −8	0.60 (0.57–0.63)	2.4 × 10 −10
Calibrationc
Omnibus test	102 (4)	4.1 × 10 −21	26 (4)	0.000034	38 (4)	1.3 × 10 −7	46 (4)	2.7 × 10 −9
Hosmer and  Lemeshow test	2.0 (8)	0.98	7.1 (8)	0.53	7.8 (8)	0.46	11 (8)	0.18
	Social Function ≥ 89a		Mental Health ≥ 81a		Physical component summary		Mental component summary
	(n = 1244)		(n = 1244)		≥ 50a (n = 1202)		≥ 50a (n = 1185)
	OR (95%CI)	p-value	OR (95%CI)	p-value	OR (95%CI)	p-value	OR (95%CI)	p-value
Pack-year 10	0.82 (0.72–0.92)	0.0011	0.77 (0.68–0.87)	0.000038	0.84 (0.74–0.95)	0.0049	0.77 (0.68–0.87)	0.000051
Box-year 10	0.98 (0.96–1.0)	0.24	0.98 (0.96–1.0)	0.25	0.96 (0.93–0.99)	0.0086	1.00 (0.97–1.0)	0.79
Female gender	0.84 (0.66–1.1)	0.17	0.87 (0.68–1.1)	0.24	0.87 (0.67–1.1)	0.31	0.80 (0.62–1.0)	0.073
Age 10 yr	1.0 (0.96–1.1)	0.31	1.2 (1.1–1.3)	0.000002	0.77 (0.70–0.85)	2.4 × 10 −7	1.3 (1.2–1.4)	1.5 × 10 −7
Model validation
Overall performance
Nagelkerke R Square	0.014		0.034		0.067		0.043
Discrimination
AUCb	0.55 (0.52–0.59)	0.0018	0.60 (0.56–0.63)	6.3 × 10 −9	0.63 (0.60–0.67)	3.6 × 10 −13	0.61 (0.57–0.64)	1.1 × 10–9
Calibrationc
Omnibus test	13 (4)	0.014	32 (4)	0.000002	58 (4)	8.0 × 10 −12	37 (4)	1.4 × 10–7
Hosmer and Lemeshow test	6.6 (8)	0.58	7.8 (8)	0.45	5.7 (8)	0.69	3.4 (8)	0.91

^aThe median for an age matched Swedish population is used as cut off, above cut off indicates better than average health

^bArea under curve (95% confidence interval) P-value to the right of the confidence interval

^cChi square (degree of freedom) P-value to the right of df