Table 2.
Criteria | Baseline TB | FU1 TB |
FU2 TB |
Median PFS | PFS-OS Association | DoR FU1 (30d) |
DoR FU2 (90d) |
---|---|---|---|---|---|---|---|
Lugano | 4,835 mm2 | 1,265 mm2 |
1,101 mm2 |
153 d |
r = 0.499 p = 0.03 |
-60.5 | -78.1% |
-2,284 mm2 | -2,338 mm2 | ||||||
Cheson | 4,835 mm2 | 1,265 mm2 | 1,101 mm2 | 169 d |
r = 0.476 p = 0.03 |
-60.5 | -78.1% |
-2,284 mm2 | -2,338 mm2 | ||||||
RECIL |
14.0 cm |
7.5 cm |
6.8 cm |
198 d |
r = 0.535 p = 0.01 |
-41.7 | -48.4% |
-4.3 cm | -6.1 cm | ||||||
LYRIC | 4,835 mm2 | 1,265 mm2 | 1,101 mm2 | 200 d |
r = 0.758 p < 0.001 |
-60.5% | -78,1% |
-2,284 mm2 | -2,338 mm2 |
Patient characteristics showing tumor burden (TB) at baseline (BL), follow-up 1 (FU1), and FU2. Median progression-free survival (PFS) is shown in days (d). The association of PFS and OS is presented as Pearson’s r. Both absolute and percentage depth of response (DoR) are reported according to each response criterion