Table 3. Induction of IL-6 secretion in BALB/c mouse spleen cell cultures by CpG DNAs.
aNucleosides shown in bold represent 3′-deoxyribonucleosides and * indicates the position of the 2′–5′-phosphorothioate internucleoside linkage. The two CpG sequence motifs used in the study are underlined. All CpG DNA is phosphorothioate modified.