Table 1.

Results of Uni- and Multivariate Cox regression for key species. Green color represents significant (<0.05) p-values and dark green color shows only a trend. Cox (M) analysis was performed only for taxa with a significant result (p < 0.1) in Cox (U) analysis. Grey colored taxa are low-abundance. For Lasso regression, Lasso coeff (n) is only shown for significant (p < 0.05) predictors.

	Cox (U) p-value	Cox (U) Wald	Cox (U) Exp (b)	Cox (M) p-value	Cox (M) Wald	Cox (M) Exp (b)	Lasso coeff (n)
Alistipes_shahii	0.0119	6.329	0.6767	0.0178	5.6203	0.6633	1.4665
Barnesiella_viscericola	0.121	2.4048	0.7057	>0.1			0.4796
Butyricimonas_faecalis	0.0785	3.0952	0.7351	>0.1			ns
Streptococcus_salivarius	0.0342	4.4852	1.2519	0.0342	4.4852	1.2519	0.5814
Bacteroides_sp_A1C1	0.3436	0.8756	0.8756	>0.1			ns
Alistipes_finegoldii	0.0228	5.1852	0.7109	>0.1			1.0919
Streptococcus_vestibularis	0.0086	6.9075	1.3859	0.0106	6.5351	1.3906	ns
Bifidobacterium_adolescentis	0.3136	1.0154	1.0815	>0.1			0.4185
Bifidobacterium_breve	0.0557	3.6602	1.4483	0.0207	5.3553	1.5452	ns
Streptococcus_parasanguinis	0.0582	3.5889	1.2927	>0.1			ns
Alistipes_dispar	0.0268	4.9062	0.7398	0.0444	4.0415	0.7421	0.9224
Streptococcus_equinus	0.0072	7.2156	1.4965	0.0024	9.229	1.6766	0.6782
Streptococcus_anginosus	0.0004	12.3796	1.7921	0.0283	4.8092	1.5541	ns
Streptococcus_gordonii	0.0596	3.549	1.3793	0.0302	4.6975	1.5568	ns
Strep._sp_FDAARGOS_192	0.0318	4.6097	1.4037	0.0047	7.9736	1.6594	ns