Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 15;6:525. doi: 10.1038/s42003-023-04897-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — a Overview of regulated innate immune sensors in the “Viral Sensors” hub, b the “Complement factors” hub and c the “Antigen presentation” hub. Bar plots of highlighted transcripts/proteins indicate median transcript level (VST) or protein SILAC ratio per stimulus and timepoint (n = 3 biological replicates). Colors indicate stimulus: TNFα (green), IFNγ (blue), TNFα + IFNγ (red). Node fill indicates response classification of transcript: TNFα (green), IFNγ (blue), TNFα + IFNγ (red), common (orange) and no classification (gray). d Confocal images of HLA-DR immunostaining in unstimulated ECs (Ctrl, pink) and stimulated with TNFα, IFNγ, and TNFα + IFNγ. HLA-DR staining is depicted in green, Hoechst staining in cyan. Representative experiment shown (n = 3 biologically independent experiments). Upper limit of the display range were adjusted equally across images for visualization purposes.