TABLE 3.
Incremental Costs and Benefits and Cost-Effectiveness Ratio for the Current Policy Compared With No Screening and No PN
| Scenario | Cumulative Costs in '000s (Discounted) ($) | Cumulative QALYs Lost in '000s (Discounted) | Incremental Costs, in ‘000s ($) | Incremental QALYs Gained, in ‘000s | ICER ($/QALY Gained) |
|---|---|---|---|---|---|
| 1. 2000–2015 | |||||
| No screening and no PN* | 15,969,000 | 1908.90 | NA | NA | NA |
| Current policy† | 21,157,000 | 1374.10 | 5,188,000 | 534.80 | 9700.8 |
| 95% Uncertainty | NA | NA | −270,670; 11,369,000 | 157.35; 1176.8 | Cost-saving; 49,478 |
| 2.1. 2016–2019 | |||||
| Current Policy† | 6,919,100 | 349.96 | NA | NA | NA |
| Guidelines‡ | 8,042,900 | 311.93 | 1,123,800 | 38.030 | 29,550 |
| 95% Uncertainty | NA | NA | 416,440; 1,938,200 | 11.383; 82.157 | 7832.8; 117,210 |
| 2.2. 2016–2019 + 5 y | |||||
| Current policy† | 14,541,000 | 738.34 | NA | NA | NA |
| Guidelines‡ | 15,494,000 | 681.35 | 953,000 | 56.990 | 16,722 |
| 95% Uncertainty | NA | NA | 202,170; 1,785,400 | 16.844; 124.58 | 2511.4; 73,877 |
Costs are in $2000 US dollars. All results are shown to 5 significant digits.
*No screening and no physician-initiated PN for 2000–2015.
†Screening coverage and PN for 2000–2015 were as estimated in the calibrated model.2 For scenarios 2.1 and 2.2, screening uptake in year 2016 and beyond was assumed to be the same as the calibrated model estimate for 2015.
‡In screening by guidelines: all sexually-active women aged 15–24 years are screened annually, and screening coverage of women 25 years and older is the same as in the “current policy” scenario. For scenario 2.2: for years 2020–2024 screening coverage as estimated in the model in 2015.