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Oral cinchonine treatment prevents body weight gain and food intake in ob/ob-GAN NASH mice (n=7). (A) Body weight (g). (B) Body weight change (%) compared to initial body weight at the onset of cinchonine treatment. (C) Average food intake (g/day). All experimental results are expressed as mean ± SEM. *p<0.05, **p<0.01, 100 mg/kg cinchonine compared with Vehicle; #p<0.05, 50 mg/kg cinchonine compared with Vehicle.
