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Oral cinchonine ameliorates hepatic steatosis and hepatic fibrosis in ob/ob-GAN NASH mice (n=7). (A and C) Representative histology of Oil Red O staining and Sirius Red staining in liver tissues (Scale bar, 50 µm). (B and D) Quantification of positive staining areas were measured by Image J software. Statistical differences were obtained using one-way ANOVA or Student’s t-test. All experimental results are expressed as mean ± SEM. **p<0.01, 100 mg/kg cinchonine compared with Vehicle.
