Table 2.
Histopathologic and immunofluorescence features
| Number of affected biopsies (n) | Percentage (%) | |
|---|---|---|
| Diffuse global glomerulosclerosis | 193/560 | 34.4 |
| Oxford classification | ||
| M | ||
| M0 | 112/339 | 33 |
| M1 | 227/339 | 67 |
| E | ||
| E0 | 258/339 | 66.1 |
| E1 | 81/339 | 23.9 |
| S | ||
| S0 | 180/339 | 53.1 |
| S1 | 159/339 | 46.9 |
| T | ||
| T0 | 227/339 | 67 |
| T1 | 96/339 | 28.3 |
| T2 | 16/339 | 4.7 |
| C | ||
| C0 | 230/339 | 67.8 |
| C1 | 60/339 | 10.7 |
| C2 | 49/339 | 8.8 |
| Haas staging | ||
| Class I | 34/560 | 6% |
| Class II | 52/560 | 9.1% |
| Class III | 50/560 | 8.8% |
| Class IV | 219/560 | 39.1% |
| Class V | 205/560 | 36.6% |
| TA | ||
| No TA | 64/560 | 11.4% |
| Mild TA (10%-25%) | 201/560 | 35.8% |
| Moderate TA (25%-50%) | 214/560 | 38.2% |
| Severe TA (>50%) | 81/560 | 14.5% |
| Immunofluorescence | ||
| IgA (3+or more) | 472/560 | 84.4% |
| IgM (2+or more) | 265/560 | 47.3% |
| C3 (2+or more) | 401/560 | 71.6% |
C=crescent, C3=complement 3, E=endocapillary hypercellularity, IgA=immunoglobulin A, IgM=immunoglobulin M, M=mesangial hypercellularity, S=segmental sclerosis, T=tubular atrophy, TA=tubular atrophy