Table 6.
Comparison of the findings of Indian studies on IgAN
| Author | Year | Sample size | Mean age (years) | Hypertension (%) | Proteinuria (nephrotic) (%) | Gross hematuria (%) | Renal failure (%) | M1 | E1 | S1 | T1 | T2 | C1/2 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bhuyan[49] | 1992 | 83 | NA | 39 | 24 | NA | 34 | NA | NA | NA | NA | NA | NA |
| Muthukumar[50] | 2002 | 98 | 25.7 | 9.2 | 25.6 | 5.1 | 13.5 | NA | NA | NA | NA | NA | NA |
| Chacko[13] | 2005 | 478 | 32 | 58 | 55 | 16 | 60 | NA | NA | NA | NA | NA | NA |
| Chandrika[14] | 2007 | 227 | 30 | 35 | 36.7 | 18.9 | 5.7 | NA | NA | NA | NA | NA | NA |
| Mittal[15] | 2012 | 66 | 29.9 | 78.8 | 23.1 | 81 (Microscopic) | NA | 79.6% | 29.6% | 57.4% | 74.2% (T1+T2) | NA | 56.6% |
| Bagchi[51] | 2012 | 103 | 28.8 | 39.4 | 63.1 | 91 (Microscopic) | 16.5 | 77.7% | 9.7% | 43.7% | 39.8% (T1+T2) | NA | 10.7% |
| Swarnlata[17] | 2019 | 3345 | 35.8 | 60.4 | 41.7 | 79.9 (Microscopic) | 78.9 | 59.3% | 38.8% | 60.3% | 20.5% | 4.2% | 29.9% |
| Alexander[52] | 2021 | 201 | 36 | 84.1 | 34 | 10 | 79.3 | 11.4% | 43.8% | 80% | 37.8% | 41.1% | 16% |
| Current study | 2020 | 560 | 32 | 69.8 | 46.8 | 4.9 | 68 | 67% | 23.9% | 46.9% | 28.3% | 4.7% | 19.5% |
C=crescent, CKD=chronic kidney disease, E=endocapillary hypercellularity, IgA=immunoglobulin A, M=mesangial hypercellularity, S=segmental sclerosis, T=tubular atrophy, UPCR, urinary protein creatinine ratio