Table 3. Immunoexpression frequencies of GLUT1, GLUT3, HK2, PFKL, PKM2, pPDH, LDHA, MCT4, and CAIX in oral potentially malignant disorders and cases of oral squamous cell carcinoma.
| Oral potentially malignant disorders | Oral squamous cell carcinoma | ||||
|---|---|---|---|---|---|
| Biomarker | n | Positive (%) | n | Positive (%) | p |
| GLUT1 | 34 | 34 (100%) | 19 | 18 (94.7%) | .358 |
| GLUT3 | 34 | 14 (41.2%) | 17 | 2 (11.8%) | .033 |
| HK2 | 34 | 14 (41.2%) | 19 | 5 (26.3%) | .279 |
| PFKL | 34 | 16 (47.1%) | 19 | 3 (15.8%) | .023 |
| PKM2 | 34 | 8 (23.5%) | 18 | 3 (16.7%) | .564 |
| pPDH | 33 | 23 (69.7%) | 19 | 8 (42.1%) | .051 |
| LDHA | 34 | 9 (26.5%) | 17 | 4 (23.5%) | .820 |
| MCT4 | 34 | 0 (0.0%) | 18 | 4 (22.2%) | .011 |
| CAIX | 34 | 2 (5.9%) | 19 | 15 (78.9%) | <0.001 |
p-Values from Pearson's chi-square or Fisher’s exact tests, for the comparison between oral potentially malignant disorders and oral squamous cell carcinoma lesions. The p-values <0.05 are in bold.