Table 2. Binding free energies between APC and telomere hybrid G4s.

G4	Stabilizer	Energy componenta
		ΔEele	ΔEvdW	ΔGGB,sol	ΔGnp,sol	−TΔS	ΔGbind
a Energies are in kcal/mol
Hybrid-I G4	APC1	350.72	−42.02	−339.48	−4.33	24.00	−11.10
	APC2	352.79	−40.41	−342.06	−4.06	23.13	−10.62
Hybrid-II G4	APC1	358.50	−62.95	−345.29	−5.54	24.08	−31.20
	APC2	374.56	−66.74	−359.98	−5.88	25.16	−32.87