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. 2023 Jan 17;19(4):827–838. doi: 10.1007/s12015-023-10508-2

Table 1.

The markers of CSCs, NSCs, and hESC

Tissues CSCs markers Resident normal stem cells markers References hESC markers (33)
Breast ALDH1, CD29, CD44, CD133, CD201, EpCAM, PODXL1, SSEA3, SSEA4, TRA-1–60, TRA-1–81, Tspan8 Axin2, CD10, CD1d, CD24, CD29, CD49f, CD49b, CD61, CD90, CD133, CK5, CK8, CK14, CK18, CK19, c-Kit, Lrp5, Lgr5, Lgr6, EpCAM, Procr, sca1, Myh11 (33–37)

ABCG2,

CD133,

CD90,

CD326,

CD24,

CD49f,

CD146,

CD10,

CD117,

CD26,

CD29,

CD9,

CD166,

Cripto1,

Notch2,

PODXL1,

SSEA1,

SSEA3,

SSEA4,

TRA-1–60,

TRA-1–81

Prostate ABCG2, ALDH1, CD29, CD44, CD49f, CD133, CD151, CD166, Sca1, TRA-1–60 CD29, CD49f, CD133, Sca1, Trop2, Lgr5 (38–42)
Lung ABCG2, ALDH1, CD44, CD56, CD133, CD166, Cripto1, Notch2, Notch3, PODXL1, SSEA1, Sox2 ABCA3, ASCL1, α-SMA, CD49f, CD271, CXCR4, GRP, KRT5, KRT8, KRT17, KRT19, LAMP3, NCAD, PDPN, ROBO, SCGB1A1, SCGB3A2, SFTPC, SMMHC, TP63, TM4SF1 (33, 43–45)
Colorectal ALDH1, CD26, CD29, CD44, CD133, CD166, Cripto1, EpCAM, Lgr5 Lgr5 (33, 46–49)
Melanoma of skin ABCB5, ALDH1, CD20, CD133, CD271, Nanog, Oct3, Oct4 CD29, CD46, CD49f, CD71, DLL1, DSG3, FRMD4A, LRIG1, MCSP (50–56)
Renal ALDH1, CD24, CD44, CD105, CD133, CXCR4, SSEA1 CD13, CD29, CD44, CD73, CD90, CD105, CD133, CD146, CD224, CK7, c-kit, NR3C2, Pax2, Pax8, SSEA4 (57–62)
Leukemia ALDH1, CD9, CD25, CD26, CD32, CD33, CD34, CD44, CD47, CD93, CD96, CD97, CD99, CD103, CD123, CLL1, IL1RAP, PODXL1, TIM3 ABCG2, CD133, CD26, CD34, CD44, CD45RA, CD49f, CD90, c-Kit, PODXL1, Sca1 (33, 63–70)
Pancreas ABCG2, ALDH1, CD133, CD9, CD24, CD44, CD49f, c-Met, CXCR1,2, CXCR4, EpCAM, GLRX3, Notch2, Nestin, Notch3, Oct3,4, PODXL1, Tspan8 Unsure markers: Cytokeratins, PDX1, Glb1 (33,71–78)