Table 7.
List of the top pathways, with the number of corresponding genes, associated with the microRNAs significantly differentially expressed between IN and TR groups. Pathways were identified from DIANA-miRPath v3.0 web server
| Selected KEGG pathways | p value | #Genes | #miRNAs |
| Cell cycle (hsa04110) | 5.01e-10 | 86 | 5 |
| p53 signaling pathway (hsa04115) | 5.77e − 08 | 52 | 6 |
| Hippo signaling pathway (hsa04390) | 9.75e−08 | 82 | 6 |
| Adherens junction (hsa04520) | 1.62e−07 | 47 | 5 |
| Protein processing in endoplasmic reticulum (hsa04141) | 7.21e−06 | 96 | 5 |
| Endocytosis (hsa04144) | 7.71e−06 | 115 | 6 |
| TGF-β signaling pathway (hsa04350) | 1.01e−05 | 51 | 6 |
| Lysine degradation (hsa00310) | 1.20e−04 | 28 | 5 |
| Thyroid hormone signaling pathway (hsa04919) | 3.34e−04 | 72 | 5 |
| FoxO signaling pathway (hsa04068) | 8.00e−04 | 76 | 5 |
| Estrogen signaling pathway (hsa04915) | 1.42e−03 | 53 | 5 |
| Erbβ signaling pathway (hsa04012) | 1.94e−03 | 55 | 6 |
| Regulation of actin cytoskeleton (hsa04810) | 3.38e−03 | 107 | 6 |
| Fatty acid metabolism (hsa01212) | 4.20e−03 | 23 | 5 |
| Focal adhesion (hsa04510) | 6.19e−03 | 107 | 5 |
| AMPK signaling pathway (hsa04152) | 1.10e−02 | 66 | 6 |
| MAPK signaling pathway (hsa04010) | 1.64e−02 | 122 | 6 |
| Phosphatidylinositol signaling system (hsa04070) | 1.65e−02 | 43 | 6 |