Table 1.
Descriptive statistics as a function of sample attrition.
| Sample | Percentage or mean | SD | n |
|---|---|---|---|
| Responders | |||
| Mean age | 52.8 | 13.8 | 608 |
| Female sex | 80.6 | 608 | |
| Mean number of strips | 1.8 | 1.1 | 608 |
| Used Venlafaxine | 41.3 | 608 | |
| Used paroxetine | 23.7 | 608 | |
| Risk factors | |||
| Fear withdrawal a | 40.0 | 608 | |
| Previous unsuccessful attempt | 52.5 | 608 | |
| Possible relapse | 6.7 | 608 | |
| Slow metaboliser b | 1.7 | 608 | |
| High dose c | 3.1 | 608 | |
| Problems when starting | 2.7 | 608 | |
| Problems when missing dose | 8.1 | 608 | |
| Antidepressant use > 2 years | 81.1 | 608 | |
| No risk factors | 6.9 | 608 | |
| Mean number of risk factors | 1.9 | 1.0 | 608 |
| Non-responders | |||
| Mean age | 46.5 | 15.4 | 3301 |
| Female sex | 72.1 | 3301 | |
| Mean number of strips | 2.2 | 1.6 | 3301 |
| Used venlafaxine | 37.0 | 3301 | |
| Used paroxetine | 18.9 | 3301 | |
| Risk factors | |||
| Fear withdrawal a | 35.0 | 3301 | |
| Previous unsuccessful attempt | 44.9 | 3301 | |
| Possible relapse | 5.8 | 3301 | |
| Slow metaboliser b | 1.2 | 3301 | |
| High dose c | 2.4 | 3301 | |
| Problems when starting | 4.2 | 3301 | |
| Problems when missing dose | 8.8 | 3301 | |
| Use longer than 2 years | 71.2 | 3221 | |
| No risk factors | 14.4 | 3301 | |
| Mean number of risk factors | 1.7 | 1.1 | 3301 |
a
Fear of starting with medication reduction because of anticipated withdrawal.
b
Patient has undergone pharmacogenetic test indicating slow/intermediate metaboliser status for current medication.
c
Dose above maximum dose as recommended in the Dutch standard (Farmacotherapeutisch Kompas).