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. 2023 May 2;13:1103013. doi: 10.3389/fonc.2023.1103013

Table 4.

Comparison of hematological and electrolyte parameters based on clinical stages.

Parameter
(Mean ± SD)
Stage I and II (lower stage) Stage III and IV (advanced stage)
Untreated
(n=57)
Treated
(n=56)
p-value Untreated
(n=43)
Treated
(n=44)
p-value
TWBC (/µL) 8.87±1.73 5.64±1.43 0.000 7.94±1.89 4.77±1.52 <0.0001
NE (/µL) 4.41±1.48 2.27±.82 0.000 3.75±1.42 1.93±.76 <0.0001
LY(/µL) 2.74±1.42 1.83±.94 0.000 2.74±1.22 1.31±.71 <0.0001
MO(/µL) 0.83±.37 0.89±.36 0.415 0.81±.38 0.82±.30 0.929
EO(/µL) 0.63±.44 0.76±.48 0.150 0.50±.33 0.73±.43 0.007
BA(/µL) 0.14±.10 0.13±.17 0.965 0.13±.15 0.15±.13 0.559
RBC(/µL) 4.54±.54 4.29±.58 0.020 4.49±.51 3.77±.60 <0.0001
Hgb (g/dL) 12.66±1.43 11.49±.71 0.000 12.27±1.05 10.56±.71 <0.0001
HCT (%) 37.76±4.34 34.16±1.92 0.000 35.98±3.23 31.56±1.93 <0.0001
RDW (%) 12.96±2.06 17.75±2.44 0.000 12.71±1.36 19.21±2.97 <0.0001
MCV (fL) 82.94±7.57 80.70±9.35 0.164 80.66±8.13 79.41±6.91 0.440
MCH (pg) 28.22±2.59 27.13±3.26 0.051 27.49±2.7 28.44±3.30 0.148
MCHC(g/dL) 33.67±.93 33.63±1.06 0.830 33.54±1.35 33.43±1.25 0.687
PLT(/µL) 272.0±81.9 313.1±119.7 0.036 210.77±50.4 451.2±145.5 <0.0001
MPV (%) 8.28±1.11 8.20±.99 0.676 8.16±1.18 7.65±1.26 0.054
PCT (%) 0.14±.04 0.19±.08 0.000 0.13±.03 0.26±.08 <0.0001
Na+(mmol/L) 142.9±4.58 133.92±4.48 0.000 141.76±4.29 132.59±7.71 <0.0001
K+ (mmol/L) 3.76±.52 4.95±.94 0.000 3.87±.48 5.57±1.13 <0.0001
Ca+2 (mg/dL) 8.82±1.03 8.93±.78 0.545 8.35±.55 8.52±1.22 0.385

TWBC, Total White Blood Cell; NE, Neutrophil; LY, Lymphocyte; MO, Monocyte; EO, Eosinophils; BA, Basophil; RBC, Red Blood Cell; Hgb, Hemoglobin; HCT, Hematocrit; RDW, Red Cell Distribution Width; MCV, Mean Cell Volume; MCH, Mean Cell Hemoglobin; MCHC, Mean Cell Hemoglobin Concentration; PLT, Platelet; MPV, Mean Platelet Volume; PCT, Plateletcrit; Na+, Sodium; Ca2+, Calcium; K+, Potassium; AC, Adriamycin-Cytoxan. Continuous variables were expressed as mean ± standard deviation (SD) and p-value < 0.05 implies a significant difference between the two study group’s variables.