Table 2.

The parameters of Formula 1 of the occurrence and development of iSNVs in BHK cells.

	K		Hillslope
	M ± SE	95 per cent CI	M ± SE	95 per cent CI
Total iSNVs	64.06 ± 1.769	60.58–67.54	0.01521 ± 0.001003	0.01323–0.01718
N-reserved iSNVs	143.6 ± 8.121	127.6–159.6	0.02036 ± 0.001616	0.01718–0.02355
N-inherited iSNVs	184.9 ± 16.89	151.7–218.2	0.01508 ± 0.001751	0.01163–0.01852
S-reserved iSNVs	356.1 ± 68.35	221.5–490.6	0.006604 ± 0.001412	0.003823–0.009384
S-inherited iSNVs	428.3 ± 79.84	271.2–585.4	0.005449 ± 0.001117	0.003251–0.007648

Y, the number of iSNVs; X, the time of passage (96 h per passage); K, a constant; HillSlope, the slope of regression curve; M, mean; SE, standard error of mean; CI, confidence interval; N, non-synonymous; and S, synonymous.