Table 2. Comparison of sociodemographic characteristics and disease data.
MS patients with pain (n=62) (100%) | MS patients without pain (n=38) (100%) | p value | MS patients with neuropathic pain (PDQ-positive) (n=18) (100%) | MS patients without neuropathic pain (PDQ-negative) (n=44) (100%) | p value | |
Age (year) | 0.253a | 0.532d | ||||
Mean±SD | 36.0±9.5 | 34.2±10.7 | 34.8±11.2 | 36.5±8.8 | ||
Median | 35.0 | 32.5 | 34.0 | 35.0 | ||
Min-Max | 19.0-60.0 | 19.0-71.0 | 19-58 | 21-60 | ||
Sex | 0.932b | 0.715c | ||||
Female | 51 (82.3%) | 31 (81.6%) | 14 (77.8%) | 37 (84.1%) | ||
Male | 11 (17.7%) | 7 (18.4%) | 4 (22.2%) | 7 (15.9%) | ||
Education level | 0.012b | 0.942b | ||||
Low | 34 (54.8%) | 11 (28.9%) | 10 (55.6%) | 24 (54.5%) | ||
High | 28 (45.2%) | 27 (71.1%) | 8 (44.4%) | 20 (45.6%) | ||
Marital status | 0.863b | 0.323b | ||||
Single | 20 (32.3%) | 13 (34.2%) | 6 (33.3%) | 14 (31.8%) | ||
Married | 37 (59.7%) | 23 (60.5%) | 12 (66.7%) | 25 (56.8%) | ||
Been married before | 5 (8.1%) | 2 (5.3%) | 0 (0%) | 5 (11.4%) | ||
Family support | 0.438b | 0.821b | ||||
Living alone | 0 (0%) | 1 (2.6%) | 0 (0%) | 0 (0%) | ||
Living with wife/husband | 40 (64.5%) | 24 (63.2%) | 12 (66.7%) | 28 (63.6%) | ||
and/or children | ||||||
Living with parents | 22 (35.5%) | 13 (34.2%) | 6 (33.3%) | 16 (36.4%) | ||
Disease duration | 0.881a | 0.489a | ||||
Mean±SD | 67.3±51.5 | 70.8±56.1 | 74.2±52.3 | 64.5±51.5 | ||
Median | 60.0 | 60.0 | 78.0 | 54.0 | ||
Min-Max | 0-214.0 | 1.0-216.0 | 1-192 | 0-214 | ||
MS type | 0.759b | 0.052b | ||||
Clinic isolated syndrome | 11 (17.7%) | 9 (23.7%) | 1 (5.6%) | 10 (22.7%) | ||
Relapsing remitting MS | 36 (58.1%) | 18 (47.4%) | 14 (77.8%) | 22 (50.0%) | ||
Progressive MS | 14 (22.6%) | 10 (26.3%) | 2 (11.1%) | 12 (27.3%) | ||
Benign MS | 1 (1.6%) | 1 (2.6%) | 1 (5.6%) | 0 (0%) | ||
Plaque locations | ||||||
Cranial | 61 (98.4%) | 38 (100%) | 0.999c | 18 (100%) | 43 (97.7%) | 0.999c |
Brainstem | 16 (25.8%) | 11 (28.9%) | 0.731b | 5 (27.8%) | 11 (25%) | 0.999c |
Cervical | 38 (61.3%) | 21 (55.3%) | 0.525b | 11 (61.1%) | 27 (61.4%) | 0.985b |
Cerebellar | 17 (27.4%) | 7 (18.4%) | 0.306b | 6 (33.3%) | 11 (25%) | 0.541c |
MS: Multiple sclerosis; PDQ: The Pain Detect Questionnaire; SD: Standard deviation; a: Mann-Whitney U test; b: Pearson’s chi-square test; c: Fisher exact test; d: Student’s t-test. |