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. 2022 Feb 16;69(1):31–39. doi: 10.5606/tftrd.2022.10524

Table 2. Comparison of sociodemographic characteristics and disease data.

  MS patients with pain (n=62) (100%) MS patients without pain (n=38) (100%) p value MS patients with neuropathic pain (PDQ-positive) (n=18) (100%) MS patients without neuropathic pain (PDQ-negative) (n=44) (100%) p value
Age (year)     0.253a     0.532d
Mean±SD 36.0±9.5 34.2±10.7   34.8±11.2 36.5±8.8  
Median 35.0 32.5   34.0 35.0  
Min-Max 19.0-60.0 19.0-71.0   19-58 21-60  
Sex     0.932b     0.715c
Female 51 (82.3%) 31 (81.6%)   14 (77.8%) 37 (84.1%)  
Male 11 (17.7%) 7 (18.4%)   4 (22.2%) 7 (15.9%)  
Education level     0.012b     0.942b
Low 34 (54.8%) 11 (28.9%)   10 (55.6%) 24 (54.5%)  
High 28 (45.2%) 27 (71.1%)   8 (44.4%) 20 (45.6%)  
Marital status     0.863b     0.323b
Single 20 (32.3%) 13 (34.2%)   6 (33.3%) 14 (31.8%)  
Married 37 (59.7%) 23 (60.5%)   12 (66.7%) 25 (56.8%)  
Been married before 5 (8.1%) 2 (5.3%)   0 (0%) 5 (11.4%)  
Family support     0.438b     0.821b
Living alone 0 (0%) 1 (2.6%)   0 (0%) 0 (0%)  
Living with wife/husband 40 (64.5%) 24 (63.2%)   12 (66.7%) 28 (63.6%)  
and/or children            
Living with parents 22 (35.5%) 13 (34.2%)   6 (33.3%) 16 (36.4%)  
Disease duration     0.881a     0.489a
Mean±SD 67.3±51.5 70.8±56.1   74.2±52.3 64.5±51.5  
Median 60.0 60.0   78.0 54.0  
Min-Max 0-214.0 1.0-216.0   1-192 0-214  
MS type     0.759b     0.052b
Clinic isolated syndrome 11 (17.7%) 9 (23.7%)   1 (5.6%) 10 (22.7%)  
Relapsing remitting MS 36 (58.1%) 18 (47.4%)   14 (77.8%) 22 (50.0%)  
Progressive MS 14 (22.6%) 10 (26.3%)   2 (11.1%) 12 (27.3%)  
Benign MS 1 (1.6%) 1 (2.6%)   1 (5.6%) 0 (0%)  
Plaque locations            
Cranial 61 (98.4%) 38 (100%) 0.999c 18 (100%) 43 (97.7%) 0.999c
Brainstem 16 (25.8%) 11 (28.9%) 0.731b 5 (27.8%) 11 (25%) 0.999c
Cervical 38 (61.3%) 21 (55.3%) 0.525b 11 (61.1%) 27 (61.4%) 0.985b
Cerebellar 17 (27.4%) 7 (18.4%) 0.306b 6 (33.3%) 11 (25%) 0.541c
MS: Multiple sclerosis; PDQ: The Pain Detect Questionnaire; SD: Standard deviation; a: Mann-Whitney U test; b: Pearson’s chi-square test; c: Fisher exact test; d: Student’s t-test.