TABLE 1.
Demographic characteristics for each cohort.
| Standard PiB | Florbetapir calibration | ||||
|---|---|---|---|---|---|
| YC‐0 | AD‐100 | YCN | ES | Insight 46 | |
| N | 34 | 45 | 13 | 33 | 432 |
| Female sex % * | — | — | 53 | 36 | 48 |
| APOE ε4: carrier/total (%) a | 8/32 (25) | 28/44 (64) | 1/10 (10) | 14/22 (63) | 129/430 (30) |
| Mean MMSE (SD) b | — | — | 29.5 (0.5) | 24.7 (5.1) | 29.2 (1.0) |
| Mean Age (SD) | 31.5 (6.3) | 67.5 (10.5) | 27.0 (4.3) | 70.2 (9.6) | 70.6 (0.7) |
Abbreviations: AD‐100, Alzheimer's disease group; APOE, apolipoprotein E; ES, elder subject group; MMSE, Mini‐Mental State Examination; PiB, Pittsburgh compound B; SD, standard deviation; YC‐0, young control group; YCN, young cognitively normal group.
a APOE ε4 carrier is defined as carrying at least one APOE ε4 allele and is unknown for the following numbers in each group: YC‐0 = 2, AD‐100 = 1, YCN = 3, ES = 11, Insight 46 = 2.
bMMSE was unknown for three participants in the YCN group. Data regarding MMSE for the Standard PiB dataset was not published in Klunk et al. 9
*Data regarding the sex of participants in the Standard PiB dataset was not published in Klunk et al. 9