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. 2023 Feb 27;15(3):361–373. doi: 10.4168/aair.2023.15.3.361

Fig. 4. Aerobic exercise down-regulated the protein expression levels of Orai and STIM1 of asthmatic rats through the IL-4-related pathway. (A) Representative Western blot images and (B-D) statistical analysis for Orai (subtype 1, 2, 3) protein expression levels of rat ASM after incubation with IL-4 (500 ng/mL, 12 hours) (n = 4), *P < 0.05, **P < 0.01 vs. the control group. (E) Representative western blot images and (F-H) statistical analysis for Orai (subtypes 1, 2 and 3) protein expression levels in the rat ASM of the model rats (n = 3), *P < 0.05, ***P < 0.001. ns indicates no significant difference. (I) Representative western blot images and (J) statistical analysis for STIM1 protein expression levels of rat ASM after incubation with IL-4 (500 ng/mL, 12 hours) (n = 3), *P < 0.05 vs. the control group. (K) Representative western blot images and (L) statistical analysis for STIM1 protein expression levels in the rat ASM of model rats (n = 3), *P < 0.05. Symbols and bars indicate the mean ± SD.

Fig. 4

IL, interleukin; ns, not significant; STIM1, stromal interaction molecule 1; ASM, airway smooth muscle.