Figure 2. Explained Proportions in the Mediation Analyses of the Effect of Tirofiban on Functional Independence Mediated by the Number of Thrombectomy Passes in the Intention-to-Treat Analysis.

The coefficients of the regression equation of each step (steps a, b, c, and c′) and the percentage of indirect effect mediated by thrombectomy passes are described. Multivariable regressions adjusted for age, pretreatment systolic blood pressure, history of diabetes, baseline NIH Stroke Scale, Alberta Stroke Program Early CT Score, and location of occlusion.