Table 2.

List of trials current in the i-CIP network and trials that have agreed to share data (total n=17 526 individuals)

Author, year	Country	Study population risk of PE/start of intervention	Intervention	Comparator	Sample size	Data already shared with the i-CIP network
Trials currently in iCIP (n=16 111 individuals, 7 trials) (data available already)
Villar,49 2006	Argentina, Egypt, India, Peru, South Africa, Vietnam	High risk, up to 20 weeks’ gestation	1500 mg calcium carbonate	Placebo	8325	Yes
Levine,50 1997	USA	Low risk, 13–21 weeks’ gestation	2000 mg calcium carbonate	Placebo	4589	Yes
Belizán,51 1991	Argentina	Any risk, 20 weeks’ gestation	2000 mg calcium carbonate	Placebo	1194	Yes
Ettinger,52 2009	Mexico	Low risk, first trimester	1200 mg calcium carbonate	Placebo	670	Yes
Goldberg,53 2013	Gambia	Any risk, 18–20 weeks’ gestation	1500 mg calcium carbonate	Placebo	662	Yes
Hofmeyr,54 2019	Argentina, South Africa, Zimbabwe	High risk, prepregnancy and up to 20 weeks’ gestation	500 mg calcium carbonate	Placebo	581	Yes
Azami,55 2017	Iran	High risk, >20 weeks’ gestation	800 mg calcium carbonate	Multivitamin	90	Yes
Trials that agreed to share IPD (n=1415 individuals, 7 trials) (data expected to be made available to us)
Omotayo,56 2018	Kenya	Low risk, 16–30 gestational weeks	1500 mg calcium carbonate	1000 mg calcium carbonate	990	No
Asemi,57 2014	Iran	Low risk, 16 weeks’ gestation	Multivitamin-mineral with 250 mg calcium	Multivitamin	104	No
Karamali,58 2016	Iran	High risk, 24–26 weeks’ gestation	1000 mg calcium carbonate, 50 000 IU vitamin D3	Placebo	60	No
Samimi,59 2016	Iran	High risk, 20 weeks’ gestation	1000 mg calcium carbonate, 50 000 IU vitamin D3	Placebo	60	No
Souza,60 2014	Brazil	High risk, 20–27 weeks’ gestation	2000 mg calcium carbonate, 100 mg aspirin	Placebo	49	No
Asemi,61 2015	Iran	High risk, 27 weeks’ gestation	800 mg calcium carbonate, 200 mg magnesium, 8 mg zinc, 400 IU vitamin D3	Placebo	46	No
Asemi,62 2016	Iran	Low risk, 25 weeks’ gestation	500 mg calcium carbonate, 200 IU vitamin D3	Placebo	46	No

i-CIP, International Calcium in Pregnancy; PE, pre-eclampsia.