Table 1.
Variable | 1-year-old participants | 2-year-old participants | ||||
Cases (n*=308) | Controls (n=292) | P-value | Cases (n=214) | Controls (n=209) | P-value | |
Age (months) (median/IQR) | 12.41 (11.48–13.66) | 12.48 (11.72–13.07) | 0.820 | 24.63 (23.87–25.46) | 23.90 (23.18–24.73) | <0.001 |
Gender male (n/%) | 174 (56.5) | 155 (53.1) | 0.401 | 116 (54.2) | 95 (45.5) | 0.072 |
Black African Race (n/%) | 308 (100) | 292 (100) | 1.00 | 214 (100.0) | 209 (100.0) | 1.00 |
Weight (kg) (median/IQR) | 9.9 (9.0–10.6) | 9.8 (8.8–10.5) | 0.118 | 12.0 (10.9–13.3) | 11.6 (10.6–12.6) | 0.007 |
Height (cm) (median/IQR) | 74 (72–77), 54–89 | 74 (72–77), 62–88 | 0.621 | 87 (85–90) | 86 (83–89) | 0.051 |
Birth weight (g) (median/IQR) | 3095 (2840–3400) | 3138 (2900–3380) | 0.124 | 3102 (2895–3400) | 3175 (2855–3445) | 0.319 |
HIV status (n/%) | ||||||
Unexposed | 229 (74.4) | 214 (73.3) | 157 (73.4) | 150 (71.8) | ||
Exposed uninfected | 67 (21.7) | 74 (25.3) | 0.101 | 45 (21.0) | 52 (24.9) | 0.531 |
Infected | 11 (3.6) | 4 (1.3) | 3 (1.4) | 1 (0.5) | ||
Unknown | 1 (0.3) | 0 (0.0) | 9 (4.2) | 6 (2.9) | ||
Underlying medical conditions (n/%) | 0 (0.0) | 0 (0.0) | N/A | 0 (0.0) | 0 (0.0) | N/A |
Age (months) at RSV† admission (median/IQR) | 4.48 (2.26–6.85) | N/A | N/A | 4.48 (2.26–6.85) | N/A | N/A |
Time (months) between RSV admission and visits (median/IQR) |
7.60 (4.77–10.68) | N/A | N/A | 20.82 (16.51–22.79) | N/A | N/A |
Duration of RSV admission (days) (median/IQR) | 2 (1-4) | N/A | N/A | 2 (1-5) | N/A | N/A |
Received supplemental oxygen during RSV admission (n/%) | 103 (34.7) | N/A | N/A | 69 (34.9) | N/A | N/A |
*n: number.
†Underlying medical conditions: congenital (ex. congenital cardiac disease, hydrocephalus), genetic (ex. trisomy 21) or medical diagnosis (ex. neurological disability, such as neuromuscular disease or cerebral palsy, hepatic abnormalities such as biliary atresia, and musculoskeletal disorders such as osteogenesis imperfecta) that may affect respiratory function.
RSV, respiratory syncytial virus.