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. 2023 May 15;14:20417314231170371. doi: 10.1177/20417314231170371

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — Schematic illustration of the fabrication of 3D bioceramic scaffolds modified with transition metal-based nanomaterials: (a) fabrication of the BGC-HM-DOX scaffold and its use in the treatment of osteosarcoma by combining photothermal therapy and chemotherapy. Hemin particles and DOX are inserted into 3D-printed BGC scaffolds using the polymer PDLLA as a medium, (b) schematic illustration of CuFeSe₂ nanocrystals growing in situ on the surface of BG scaffolds and their dual function of anti-tumor treatment and tissue regeneration, (c) fabrication of high-strength Fe-CaSiO₃ scaffold and their potential use in synergetic photothermal-chemodynamic anti-tumor therapy and concurrent osteogenesis promotion, (d) the photothermal osteosarcoma ablation process and bone regeneration of NBGS are shown schematically. Vascularization can also be promoted to facilitate osseous reconstruction. Cited with permission.¹² Copyright 2021, Chemical Engineering Journal.⁹⁹ Copyright 2018, Biomaterials.¹¹⁹ Copyright 2018, NPG Asia Materials.¹⁰⁴ Copyright 2021, Nano-Micro Lett.