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. 2023 Mar 20;22(5):e13818. doi: 10.1111/acel.13818

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© 2023 The Authors. Aging Cell published by Anatomical Society and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Biological actions and indirect effects of glucagon‐like peptide 1. Major direct and indirect effects of glucagon‐like peptide‐1 (GLP‐1) in humans across organ systems. Both confirmed and potential effects are shown. The GLP‐1 receptor agonist (RA) semaglutide is shown bound to the GLP‐1 receptor (GLP‐1R). Created with BioRender.com.