Table I.
Sociodemographic and Clinical Characteristics of children admitted to CHCO with RSV, influenza, or COVID-19 from October 1, 2021, to April 30, 2022
| Sociodemographic and clinical characteristics | All cases (n = 837) | RSV (n = 487 [58.2%]) | COVID-19 (n = 303 [36.2%]) | Influenza (n = 47 [5.6%]) | P value |
|---|---|---|---|---|---|
| Age, median (IQR) | 1.5 (0.4-4.1) | 1.0 (0.2-2.4) | 2.7 (0.6-10.1) | 7.1 (2.9-9.6) | <.0001 |
| Age | <.0001 | ||||
| <6 months | 248 (29.6) | 183 (37.6) | 64 (21.1) | 1 (2.1) | |
| 6 months-1 year | 217 (25.9) | 146 (30.0) | 65 (21.5) | 6 (12.8) | |
| 2 years-4 years | 196 (23.4) | 123 (25.3) | 60 (19.8) | 13 (27.7) | |
| 5 years-11 years | 103 (12.3) | 30 (6.2) | 55 (18.2) | 18 (38.3) | |
| 12 years-17 years | 73 (8.7) | 5 (1.0) | 59 (19.5) | 9 (19.2) | |
| Female sex | 375 (44.8) | 213 (43.7) | 136 (44.9) | 26 (55.3) | .31 |
| Race/ethnicity | .03 | ||||
| American Indian/Alaska Native | 4 (0.5) | 1 (0.2) | 2 (0.7) | 1 (2.1) | |
| Asian/Pacific Islander | 25 (3.0) | 19 (3.9) | 5 (1.7) | 1 (2.1) | |
| Black | 63 (7.5) | 30 (6.2) | 28 (9.2) | 5 (10.6) | |
| Hispanic/Latinx | 280 (33.4) | 153 (31.4) | 106 (35.0) | 21 (44.7) | |
| Multiracial | 15 (1.8) | 7 (1.4) | 7 (2.3) | 1 (2.1) | |
| White | 371 (44.3) | 226 (46.4) | 134 (44.2) | 11 (23.4) | |
| Unknown | 79 (9.4) | 51 (10.5) | 21 (6.9) | 7 (14.9) | |
| Insurance status | <.0001 | ||||
| Government Insurance | 461 (55.1) | 238 (48.9) | 191 (63.0) | 32 (68.1) | |
| Private | 350 (41.8) | 239 (49.1) | 98 (32.3) | 13 (27.7) | |
| Uninsured | 10 (1.2) | 3 (0.6) | 5 (1.7) | 2 (4.3) | |
| Unknown | 16 (1.9) | 7 (1.4) | 9 (3.0) | 0 (0) | |
| Underlying medical conditions | |||||
| At least 1 underlying medical condition | 358 (42.8) | 179 (36.8) | 152 (50.2) | 27 (57.5) | <.0001 |
| Prematurity | 97 (27.1) | 77 (43.0) | 19 (12.5) | 1 (3.7) | <.0001 |
| Chronic lung disease | 142 (39.7) | 60 (33.5) | 65 (42.8) | 17 (63.0) | .0084 |
| Asthma/RAD | 96 (26.8) | 37 (20.7) | 44 (29.0) | 15 (55.6) | .0005 |
| Chronic respiratory failure | 12 (3.4) | 7 (3.9) | 5 (3.3) | 0 (0) | .57 |
| Obstructive sleep apnea | 29 (8.1) | 11 (6.2) | 16 (10.5) | 2 (7.4) | .34 |
| Oxygen dependent | 33 (9.2) | 19 (10.6) | 14 (9.2) | 0 (0) | .21 |
| Chronic metabolic disease | 23 (6.4) | 7 (3.9) | 15 (9.9) | 1 (3.7) | .07 |
| Blood disorders/hemoglobinopathy | 21 (5.9) | 9 (5.0) | 12 (7.9) | 0 (0) | .22 |
| Cardiovascular disease | 67 (18.7) | 36 (20.1) | 30 (19.7) | 1 (3.7) | .11 |
| Neurological disorder | 97 (27.1) | 38 (21.2) | 52 (34.2) | 7 (25.9) | .03 |
| Immunocompromised condition | 23 (6.4) | 4 (2.2) | 19 (12.5) | 0 (0) | .0003 |
| History of transplant | 3 (0.8) | 1 (0.6) | 2 (1.3) | 0 (0) | .67 |
| Gastrointestinal/liver disease | 4 (1.1) | 2 (1.1) | 2 (1.3) | 0 (0) | .84 |
| Renal disease | 6 (1.7) | 1 (0.6) | 4 (2.6) | 1 (3.7) | .24 |
| Dialysis | 3 (0.8) | 1 (0.6) | 2 (1.3) | 0 (0) | <.0001 |
| Rheumatologic condition | 2 (0.6) | 0 (0) | 2 (1.3) | 0 (0) | .35 |
| Obesity | 24 (6.7) | 3 (1.7) | 17 (11.2) | 4 (14.8) | .0006 |
| Hypertension | 6 (1.7) | 0 (0) | 5 (3.3) | 1 (3.7) | .047 |
| Feeding tube dependent | 58 (16.2) | 25 (14.0) | 32 (21.1) | 1 (3.7) | .04 |
| Trach/vent dependent | 9 (2.5) | 5 (2.8) | 4 (2.6) | 0 (0) | .68 |
| Wheelchair dependent | 6 (1.7) | 1 (0.6) | 5 (3.3) | 0 (0) | .12 |
| Abnormality of airway | 22 (6.2) | 10 (5.6) | 12 (7.9) | 0 (0) | .26 |
| Chronic lung disease of prematurity | 29 (8.1) | 17 (9.5) | 11 (7.2) | 1 (3.7) | .52 |
Values are number (%) unless otherwise noted.