Figure 3.

FBXW7 promoted apoptosis and autophagy in CAL27 cells. CAL27 were transfected with LV‐FBXW7 for 72 h. The protein level of proapoptotic molecules BAX, BAK and antiapoptotic molecules MCL1 and BCL2 were examined by western blot (A). The autophagy‐related protein levels of Beclin1, Atg7 and LC3 were examined by western blot (B). The expressions were normalized to control (C–I). The data were shown as median (interquartile range). *p < .05; **p < .01; ***p < .001 compared with control. The experiments were performed in triplicate to confirm the results.