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[Preprint]. 2023 Sep 17:2023.05.02.539023. Originally published 2023 May 2. [Version 2] doi: 10.1101/2023.05.02.539023

Figure 7. Comparison of structures predicted by AlphaFold2-multimer with and without transmembrane and cytoplasmic domains.

Figure 7.

(A) Full-length structures of certain integrins calculated by Alphafold2-multimer exhibit artificial contacts between the ectodomain and TM-CT domains. (B) The integrins shown in panel A were re-modeled by AlphaFold2-multimer in the absence of TM-CT domains. The structures were superimposed based on the calf-2 domain of the α subunit and are presented in the same orientation. The α and β subunits are shown in wheat and magenta, respectively.