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[Preprint]. 2023 Sep 17:2023.05.02.539023. Originally published 2023 May 2. [Version 2] doi: 10.1101/2023.05.02.539023

Figure 8. Comparison of selected structures predicted by AlphaFold2-multimer with and without enabling the option to use known structures as templates.

Figure 8.

(A) Full-length α5β1 structures were calculated by AlphaFold2-multimer with the max_template_date set to either year 2023 or 2000. Crystal structure of αIIbβ3 (PDB 3FCS) and the cryo-EM structure of α5β1 (PDB 7NXD) were provided for comparison. (B) AlphaFold2 structures of full-length α10β1 with the max_template_date set to either year 2023 or 2000. (C) Full-length αVβ8 structures modeled by by AlphaFold2-multimer with the max_template_date set to either year 2023 or 2000. (D) AlphaFold2 structures of ectodomain of αXβ2. The crystal structure of αXβ2 (PDB 4NEH) was shown for comparison.