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[Preprint]. 2023 May 2:2023.05.01.538955. [Version 1] doi: 10.1101/2023.05.01.538955

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Figure 6: — Differential RBD IgG glycosylation impacts antibody functional potency more in infant cord compared to maternal responses. For every patient sample, potency was calculated for each antibody function. The medians (bars), interquartile ranges (boxes), and ranges (whiskers) of the Z-scored data for (A, left) cord and (B, left) maternal samples in each clinical group are shown. Heatmap of the regression coefficients (r²) summarizes the dependency of RBD-specific antibody functions on RBD-specific IgG glycans in (A, right) cord and (B, right) maternal samples by simple linear regression. Fucosylated (F), monogalactosylated (G1), digalactosylated (G2), monosialylated (S1), disialylated (S2) and bisecting n-acetyl-glucosamine (B) glycoforms are shown. * p≤0.05; ** p≤0.01; *** p≤0.001; **** p≤0.0001.