Figure 3.

Altered frequencies and distributions of Lys⁺ revertants in mutant backgrounds. Mean frequencies of Lys⁺ colonies are shown; error bars are 95% confidence intervals for the means. The overall distribution of the five major NHEJ types in each mutant background was compared to WT using a 2 × 5 contingency chi square test (ns, not significant). If the global p value (above each spectrum) was less than 0.05, individual mutation classes were compared using the Bonferroni correction to determine significance (p<0.05/5); asterisks indicate a significant proportional increase/decrease.