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[Preprint]. 2023 May 5:2023.05.04.539439. [Version 1] doi: 10.1101/2023.05.04.539439

Figure 1. Effect on lifespan of post-developmental TDP-43 overexpression in individual glial cell types of the Drosophila CNS.

Figure 1.

(A) To induce post development expression of both hTDP-43 and 5XUAS-Unc84–2XGFP, flies were reared at 21°C and shifted to 29°C upon eclosion (day 0). (B-F) Lifespan analyses with expression in each individual glial cell type, compared to a control without TDP-43; p<0.0001. (G) Lifespan analysis for pan-glial TDP-43 expression compared to a control without TDP-43; p<0.0001. Gal4 lines and full genotypes used for each cell type are listed in methods.