Table 2.

Results of cross-sectional and longitudinal analyses of the associations between serum adiponectin and global Aβ retention in cognitively normal individuals.

	Global Aβ retention, SUVR		Δ global Aβ retention, SUVR
	β	p-value	β	p-value
Independent variable: adiponectin
Model 1a	0.276	<0.001***	0.171	0.031*
Model 2b	0.230	<0.001***	0.168	0.038*
Model 3c	0.248	0.004**	0.230	0.022*

Aβ=beta-amyloid, =standardized beta coefficients.

^aNot adjusted.

^bAdjusted for age, sex, and APOE4.

^cAdjusted for age, sex, APOE 4, education, GDS score, VRS, BMI, annual income, LPA, albumin, fasting glucose, HDL- and LDL-cholesterol, HOMA-IR, zinc, alcohol intake, and smoking.

^*p < 0.05,

^**p < 0.01,

^***p < 0.001.