Table 8.

Results of cross-sectional and longitudinal analyses of the associations between serum adiponectin and global Aβ retention in cognitively normal individuals according to age.

	Global Aβ retention, SUVR		Δ global Aβ retention, SUVR
	β	p-value	β	p-value
Independent variable: adiponectin under high age (≥65 years) (n = 191, 137)
Model 1a	0.292	<0.001***	0.231	0.016 *
Model 2b	0.305	<0.001***	0.240	0.013 *
Model 3c	0.302	0.003**	0.327	0.007**
Independent variable: adiponectin under low age (< 65 years) (n = 92, 70)
Model 1a	-0.107	0.398	-0.170	0.228
Model 2b	-0.153	0.234	-0.164	0.267
Model 3c	-0.141	0.444	-0.249	0.238

Aβ=beta-amyloid, =standardized beta coefficients.

^aNot adjusted.

^bAdjusted for sex, and APOE4.

^cAdjusted for sex, APOE 4, education, GDS score, VRS, BMI, annual income, LPA, albumin, fasting glucose, HDL- and LDL-cholesterol, HOMA-IR, zinc, alcohol intake, and smoking.

^*p < 0.05,

^**p < 0.01,

^***p < 0.001.