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. 2023 Apr 4;66(4):1208–1239. doi: 10.1044/2022_JSLHR-22-00510

Table 3.

The p value of the likelihood ratio test of the mixed-effects model comparing the overall TD versus DS frequency developmental trajectories with and without accounting for the physical characteristics of the DS phenotype as specified in the text.

p values for differences between DS and TD speaker groups
Adjusted for age and sex only
Adjusted for age, sex, and physical characteristics
Frequency /i/ /u/ /æ/ /ɑ/ /i/ /u/ /æ/ /ɑ/
f o .0000 .0000 .0007 .0009 .0030 .0006 .0118 .0036
F1 .0000 .0002 .0000 .0044 .0000 .0079 .0000 .0085
F2 .0326 .0000 .0000 .0000 .0111 .0000 .0000 .0000
F3 .0366 .4931 .0056 .0001 .1283 .3517 .0205 .0001
F4 .0024 .1561 .1792 .1223 .0226 .0550 .1486 .0547

Note. p values smaller than the Bonferroni-corrected significance value of .0025 are shown in bold. TD = typically developing; DS = Down syndrome; f o = fundamental frequency.