. Author manuscript; available in PMC: 2023 May 16.

Published in final edited form as: J Pediatr. 2022 May 14;247:38–45.e5. doi: 10.1016/j.jpeds.2022.05.016

Table 2.

Structural and functional abnormalities at any time after birth, Pediatric Outcomes of Prenatal Zika Exposure study, Puerto Rico, 2017–2020.

Abnormalities	n/N (%)

Microcephaly	1/97 (1.03)
Auditory brainstem response	0/31 (0)
Failure to thrive^*	2/97 (2.06)
Possible visual impairment	17/97 (17.53)
Pediatric assessment	3/97 (3.09)
Instrument-based screening	14/69 (20.29)
Contractures	1/97 (1.03)
Seizures	3/97 (3.09)
Motor tone & function
Hypotonia	32/97 (32.99)
Hypertonia	8/97 (8.25)
Both hypotonia/hypertonia	2/97 (2.06)
Abnormal movements^†	7/97 (7.22)
Tremors^†	14/97 (14.43)
Abnormal posturing^†	7/97 (7.22)
Swallowing difficulties^†	8/97 (8.25)
Developmental risk or delay
Parental report (ASQ-3), any domain in the first year	16/74 (21.62)
Parental report (ASQ-3), any domain in the second year	29/60 (48.33)
Parental report (ASQ-3), any domain in the third year	34/61 (55.74)
Professional assessment (BSID-III), any domain in the second year	33/53 (62.26)
Professional assessment (BSID-III), any domain in the third year	17/47 (36.17)

Height z-scores < −2 and weight or weight/height z-scores < −2.

^†

Parental report.