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. 2023 Apr 1;13(2):e2023107. doi: 10.5826/dpc.1302a107

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©2023 Gualdi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited.

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(A–D) Summary of the main features imaged by in vivo reflectance confocal microscopy (RCM) (Vivascope 3000) in RCM in Inflammatory Linear Verrucous Epidermal Nevus.

(A) Spongiosis (withe circle) with a pattern closer to the honeycombed one with thickened, highly refractive intercellular space between keratinocytes.

(B) Presence of a single roundish refractive Demodex folliculorum (arrow) within the hair follicles and a pattern closer to the honeycombed.

(C) At level of the epithelial-connective tissue junction, non-rimed connective tissue papillae were observed.

(D) Below the basal layer, connective tissue papillae appeared disrupted and confluent in large dark areas (white circle), peculiar signs of the interface dermatitis.