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. 2023 May 17. Online ahead of print. doi: 10.1016/j.jinf.2023.05.012

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© 2023 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — Azvudine versus Paxlovid for oral treatment of COVID-19 patients with pre-existing comorbidities. A) Composite and individual outcomes in Azvudine and Paxlovid groups. B) Cumulative incidence of composite disease progression outcomes for Azvudine versus Paxlovid recipients. C) The effectiveness of Azvudine versus Paxlovid in reducing the risk of composite disease progression outcome by subgroups of selected baseline characteristics. Abbreviation, COPD, chronic obstructive pulmonary disease.