Table 1.

Demographics and baseline characteristics

	HNC + LED patients (N = 521)
Age (years)
Mean (SD)	58.0 ± 9.6
Groups
18–34	8 (1.5%)
35–44	27 (5.2%)
45–54	131 (25.1%)
55–64	275 (52.8%)
65–74	48 (9.2%)
≥ 75	32 (6.1%)
Sex
Female	12 (23.2%)
Male	509 (76.8%)
LED-Associated Conditions
Iliac vein disorders (May-Thurner syndrome)	10 (0.2%)
Cellulitis	17 (3.3%)
Deep vein thrombosis	24 (4.6%)
Other infections	287 (55.1%)
Comorbidity Profile
Depression	162 (31.1%)
Diabetes	81 (15.5%)
Heart failure	13 (2.5%)
With beta blocker therapy	9 (1.7%)
Without beta blocker therapy	4 (0.8%)
Hypertension	265 (50.9%)
Obesity	51 (9.8%)
Renal disease	60 (11.5%)
Use of Selected Drugs or Procedures
Diuretics	101 (19.4%)
Dressings for venous leg ulcers	15 (2.9%)
Anti-inflammatory agents	251 (48.2%)
Lymphoscintigraphy	2 (0.4%)
Cancer Treatment
Chemotherapy	330 (63.3%)
Radiation	350 (67.2%)
Surgery	241 (46.3%)
Year of Index Date
2013–2014	127 (24.4%)
2015–2016	189 (36.3%)
2017–2018	205 (39.3%)