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. 2023 May 16;14:2241. doi: 10.1038/s41467-023-37714-3

Fig. 2. The CRISPR screen identifies genes and pathways required for AMA toxicity.

Fig. 2

a Bubble plot of p value from AMA screen. b Distribution of Log2 fold change (LFC, AMA treatment versus control) for each gene. c The p value and LFC of significant 559 genes. The top 10 genes were highlighted and marked. d, e GO terms enrichment analysis of these significant hits for biological process d and molecular function e. f KEGG pathway analysis of these significant hits. g Genetic interaction network of the significant 559 genes. The node size represents the -Lg (RRA score). Source data are provided as a Source Data file.