Table 2.
Control | PBS + DOX | M-Mito + DOX | |
---|---|---|---|
Diameter; s | 1.88 ± 0.25 | 2.29 ± 0.43 | 1.69 ± 0.30## |
Diameter; d | 3.45 ± 0.28 | 3.47 ± 0.42 | 3.21 ± 0.21 |
Volume; s | 11.64 ± 3.55 | 19.01 ± 8.92∗ | 8.91 ± 3.86# |
Volume; d | 50.02 ± 9.87 | 50.92 ± 14.95 | 41.78 ± 6.47 |
Stroke volume | 38.37 ± 7.82 | 31.91 ± 6.27 | 32.87 ± 4.31 |
Ejection fraction | 78.29 ± 4.37 | 64.2 ± 6.53∗∗ | 78.19 ± 8.09## |
Fractional shortening | 46.72 ± 4.26 | 34.39 ± 4.44∗∗ | 46.38 ± 7.99## |
Cardiac output | 15.83 ± 3.33 | 13.29 ± 2.6 | 14.01 ± 1.78 |
LV mass | 96.98 ± 10.5 | 93.05 ± 30.31 | 98.22 ± 18.21 |
LV mass cor | 77.58 ± 8.4 | 74.44 ± 24.25 | 78.57 ± 14.57 |
LVAW; s | 1.37 ± 0.12 | 1.19 ± 0.22 | 1.54 ± 0.23## |
LVAW; d | 0.88 ± 0.14 | 0.79 ± 0.22 | 1 ± 0.1 |
LVPW; s | 1.4 ± 0.08 | 1.16 ± 0.14∗∗ | 1.3 ± 0.11# |
LVPW; d | 0.760.08 | 0.76 ± 0.08 | 0.79 ± 0.08 |
Compared with the control group: ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.
Compared with the PBS + DOX group: #p < 0.05; ##p < 0.01; ###p < 0.001.