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. 2023 Feb 18;31(5):1468–1479. doi: 10.1016/j.ymthe.2023.02.016

Table 2.

Cardiac function of control, PBS + DOX, and M-Mito + DOX animals

Control PBS + DOX M-Mito + DOX
Diameter; s 1.88 ± 0.25 2.29 ± 0.43 1.69 ± 0.30##
Diameter; d 3.45 ± 0.28 3.47 ± 0.42 3.21 ± 0.21
Volume; s 11.64 ± 3.55 19.01 ± 8.92∗ 8.91 ± 3.86#
Volume; d 50.02 ± 9.87 50.92 ± 14.95 41.78 ± 6.47
Stroke volume 38.37 ± 7.82 31.91 ± 6.27 32.87 ± 4.31
Ejection fraction 78.29 ± 4.37 64.2 ± 6.53∗∗ 78.19 ± 8.09##
Fractional shortening 46.72 ± 4.26 34.39 ± 4.44∗∗ 46.38 ± 7.99##
Cardiac output 15.83 ± 3.33 13.29 ± 2.6 14.01 ± 1.78
LV mass 96.98 ± 10.5 93.05 ± 30.31 98.22 ± 18.21
LV mass cor 77.58 ± 8.4 74.44 ± 24.25 78.57 ± 14.57
LVAW; s 1.37 ± 0.12 1.19 ± 0.22 1.54 ± 0.23##
LVAW; d 0.88 ± 0.14 0.79 ± 0.22 1 ± 0.1
LVPW; s 1.4 ± 0.08 1.16 ± 0.14∗∗ 1.3 ± 0.11#
LVPW; d 0.760.08 0.76 ± 0.08 0.79 ± 0.08

Compared with the control group: ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.

Compared with the PBS + DOX group: #p < 0.05; ##p < 0.01; ###p < 0.001.