TABLE 3.

miRNA as diagnostics markers for radiation and immunotherapy.

MiRNA	Regulation	Therapeutic utility	References
Radiotherapy
miR-301a, miR-18b, miR-141	Downregulation	Tolerance to RT marker	Chen et al. (2022a)
miR-1323, miR-34c-5p, miR-371a-5p	Upregulation	Tolerance to RT marker	Chen et al. (2022b)
miR-200a, miR-93	Upregulation	Therapy assessment following radiation	Chen et al. (2022a)
miR-29b, miR-16, miR-1254, miR-150	Upregulation	Tolerance to RT marker	Hutchinson et al. (2020)
miR-296-5p	Upregulation	Tolerance to RT marker	Maia et al. (2015)
Immunotherapy
Let-7 family	Downregulation	Immunotherapy predictive marker	Yu et al. (2019)
miR-28-5p, miR-21-5p, miR-199a-3p	Downregulation	Immunotherapy predictive marker	Li et al. (2018)
miR-28-5p, miR-21-5p, miR-200c-3p	Downregulation	Marker of the anti-PD-1/PD-L1 therapy responsiveness	Shukuya et al. (2020)