Table 3.
The hematological response and organ response in all patients and subgroups.
| All patients N=89 |
ECV > 40% N=45 |
ASCT (ECV > 40%) N=24 |
Chemotherapy (ECV > 40%) N=21 |
P value | |
|---|---|---|---|---|---|
| Hematological response | |||||
| ORR % (n) | 83.8 (57/68) | 78.4 (29/37) | 90.5 (19/21) | 62.5 (10/16) | 0.055 |
| CR % (n) | 50.0 (34/68) | 40.5 (15/37) | 47.6 (10/21) | 31.3 (5/16) | 0.315 |
| VGPR % (n) | 25.0 (17/68) | 27.0 (10/37) | 33.3 (7/21) | 18.8 (3/16) | 0.538 |
| PR % (n) | 8.8 (6/68) | 10.8 (4/37) | 9.5 (2/21) | 12.5 (2/16) | 1.000 |
| NR % (n) | 16.2 (11/68) | 21.6 (8/37) | 9.5 (2/21) | 37.5 (6/16) | 0.055 |
| Organ response | |||||
| Cardiac % (n) | 65.4 (34/52) | 59.0 (23/39) | 77.3 (17/22) | 35.3 (6/17) | 0.008 |
| Renal % (n) | 67.5 (54/80) | 57.5 (23/40) | 75.0 (18/24) | 31.3 (5/16) | 0.006 |
ASCT, autologous stem cell transplantation; ORR, overall response rate; CR, complete response; VGPR, very good partial response; PR, partial response; NR, no response